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SASInstitute A00-282 : Clinical Trials Programming Using SAS 9.4

A00-282

Exam Code: A00-282

Exam Name: Clinical Trials Programming Using SAS 9.4

Updated: Aug 27, 2026

Q & A: 144 Questions and Answers

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SASInstitute A00-282 Exam Syllabus Topics:

SectionWeightObjectives
Topic 1: Clinical Trials Data Structures10%- CDISC standards: SDTM, ADaM
- Clinical domain structures
- Define.xml and dataset specifications
Topic 2: Apply Statistical Procedures for Clinical Trials15%- PROC MEANS, FREQ, TABULATE
- Basic statistical analysis for clinical data
Topic 3: Clinical Trials Process5%- Clinical trial lifecycle and protocol
- Derive programming requirements from protocol and CRF
Topic 4: Report Clinical Trials Results10%- PROC REPORT and PROC PRINT
- Produce tables, listings, and figures
Topic 5: Regulatory Submissions5%- ICH and FDA guidelines
- Compliance for clinical data reporting
Topic 6: Macro Programming for Clinical Trials15%- Macro variables and parameters
- Debugging macros
- Create and call macros
Topic 7: Transform or Summarize Clinical Trials Data15%- Data step manipulation
- Derive variables and study days
- Aggregation and transposition
Topic 8: Manage Clinical Trials Data5%- Access and explore clinical datasets
- Use SQL and dictionary tables
- Clean, merge, and subset data
Topic 9: Validate Clinical Trial Data Reporting20%- Use PROC COMPARE and log review
- Validation principles
- Programming validation techniques

SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:

Question 1

Given an existing work data set (DM), the following code is submitted:

A. MPRINT
B. MRECALL
C. MLOGIC
D. SYMBOLGEN


Question 2

Which two variables are required in BDS ADaM data sets?
(Choose two.)

A. PARAM
B. AVAL
C. STUDYID
D. ASEQ


Question 3

Which two SDTM domains store information for the experimental design of the trial?
(Choose two.)

A. TA
B. TD
C. TE
D. TV


Question 4

Review the following procedure format:
PROC TTEST date=date;
class group-variable;
var variable;
run;
What is the required type of data for the variable in this procedure?

A. Character
B. Categorical
C. Treatment
D. Continuous


Question 5

In a Statistical Analysis Plan (SAP) the following statement is written:
To test the association between the pain intensity reported by the patient and the treatment the patient has been administered, a Cochran-Mantel-Haenszel test will be performed adjusting for the country of the patient's investigational site.
The following variables and levels are used:
- Pain intensity (PAIN): "No pain", "Mild pain", "Moderate pain", "Severe pain", "Most severe pain"
- Treatment group (TREAT): "Placebo", "Drug A", "Drug B"
- Country (COUNTRY): Eight different values.
The following program is written to perform this analysis:
proc freq data=pain;
by COUNTRY;
tables PAIN * TREAT / cmh;
run;
This code does not produce the analysis requested by the SAP.
What is wrong with this code?

A. The variable COUNTRY should be on the TABLES statement instead of the BY statement.
B. The variables PAIN and TREAT should be on the BY statement, and the variable COUNTRY should be on the TABLES statement.
C. The option CMH should be on the PROC FREQ statement instead of on the TABLES statement.
D. The variable PAIN should be on the BY statement along with the variable COUNTRY.


Solutions:

Question 1
Answer: C
Question 2
Answer: A,C
Question 3
Answer: A,C
Question 4
Answer: D
Question 5
Answer: A

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